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WYE-125132 (WYE-132)


mTOR Inhibitor

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Catalog No. A11038

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
WYE-125132 5mg A11038-5

Regular Price: $120.00

Special Price: $108.00

WYE-125132 10mg A11038-10

Regular Price: $200.00

Special Price: $180.00

WYE-125132 50mg A11038-50

Regular Price: $720.00

Special Price: $648.00

WYE-125132 100mg A11038-100

Regular Price: $1,200.00

Special Price: $1,080.00

WYE-125132 (WYE-132) 10mM * 1mL in DMSO A11038-10mM-D

Regular Price: $135.00

Special Price: $121.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).

WYE-125132 (WYE-132)

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Chemical Information

Catalog Num A11038
Actions Inhibitor
M. Wt 519.6
Formula C27H33N7O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1144068-46-1
Synonyms WYE125132, WYE-132, WYE132
Chemical Name N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea

Biological Activity

WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).
0.19 nM


Solubility (25°C) * In vitro DMSO 104 mg/mL (200.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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