XL-888 ON SALE HSP90 Inhibitor

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Catalog No. A11251

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
XL-888 5mg A11251-5

Regular Price: $110.00

Special Price: $93.50

XL-888 10mg A11251-10

Regular Price: $200.00

Special Price: $170.00

XL-888 25mg A11251-25

Regular Price: $400.00

Special Price: $340.00

XL-888 50mg A11251-50

Regular Price: $700.00

Special Price: $595.00

XL-888 10mM * 1mL in DMSO A11251-10mM-D

Regular Price: $170.00

Special Price: $144.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.

XL-888

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Chemical Information

Catalog Num A11251
Actions Inhibitor
M. Wt 503.63
Formula C29H37N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1149705-71-4
Synonyms XL888; XL-888; XL 888
SMILES code CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[[email protected]]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5
Chemical Name 5-((R)-sec-butylamino)-N1-((1R,3s,5S)-8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylterephthalamide

Biological Activity

Description
XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
HSP90
24 nM

Solubility

Solubility (25°C) * In vitro DMSO 100 mg/mL (198.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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