7,8-Dihydroxyflavone

Catalog No.: A16123

TrkB agonist

7,8-Dihydroxyflavone

7,8-Dihydroxyflavone Chemical Structure

CAS NO. 38183-03-8

7,8-Dihydroxyflavone, a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension.

Availability: In stock

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5 mg
$40.00
50 mg
$80.00
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Biological Activity

7,8-Dihydroxyflavone, a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension.
Targets
TrkB receptor
320 nM(Kd)
In vitro DMSO 44 mg/mL (173.06 mM)
Water Insoluble
Ethanol 1 mg/mL (3.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.33 mL 196.66 mL 393.33 mL
0.5 mM 7.87 mL 39.33 mL 78.67 mL
1 mM 3.93 mL 19.67 mL 39.33 mL
5 mM 0.79 mL 3.93 mL 7.87 mL

*The above data is based on the productmolecular weight 254.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16123
Actions Agonist
CAS No. 38183-03-8
Formula C15H10O4
M. Wt 254.24
Solubility DMSO
Purity >98%
Synonyms 7,8-DHF
SMILES OC1=C(C2=CC=C1O)OC(C3=CC=CC=C3)=CC2=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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