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7,8-Dihydroxyflavone

TrkB agonist

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Catalog No. A16123

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
7,8-Dihydroxyflavone 5mg A16123-5
$90.00
7,8-Dihydroxyflavone 10mg A16123-10
$160.00
7,8-Dihydroxyflavone 50mg A16123-50
$680.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

7,8-Dihydroxyflavone, a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension.

7,8-Dihydroxyflavone

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Chemical Information

Catalog Num A16123
Actions Agonist
M. Wt 254.24
Formula C15H10O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 38183-03-8
Synonyms 7,8-DHF
SMILES OC1=C(C2=CC=C1O)OC(C3=CC=CC=C3)=CC2=O

Biological Activity

Description
7,8-Dihydroxyflavone, a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension.
Targets
TrkB receptor
320 nM(Kd)

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.33 mL 196.66 mL 393.33mL
0.5 mM 7.87 mL 39.33 mL 78.67 mL
1 mM 3.93 mL 19.67 mL 39.33 mL
5 mM 0.79 mL 3.93 mL 7.87 mL

*The above data is based on the productmolecular weight 254.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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