Catalog No.
Product Name
Application
Product Information
Citations
-
Guanfacine Derivative
Etiguanfacine is a derivative of Guanfacine that primarily targets alpha-2 adrenergic receptors. It exhibits potential for reducing gastrointestinal side effects commonly associated with Guanfacine, making it a valuable tool for research into improved therapeutic profiles. This compound can be utilized in studies involving hypertension and attention-deficit hyperactivity disorder (ADHD), as well as in evaluating receptor-mediated mechanisms in neuropharmacology. -
Drug Derivative
Fepradinol is a drug derivative that primarily acts as a selective modulator of adrenergic receptors. This compound exhibits significant biological activity in influencing cardiovascular responses and can be utilized in research focused on cardiovascular pharmacology. Its modulatory effects make it valuable for investigating the therapeutic potential in treating various cardiovascular disorders. -
Drug Derivative
Methoserpidine is a drug derivative that primarily functions as an antagonist of the alpha-adrenergic receptor. This compound exhibits significant biological activity in modulating cardiovascular responses and neurotransmitter release, making it useful for research in hypertension and other cardiovascular disorders. Its properties enable exploration of adrenergic signaling pathways and may provide insights into potential therapeutic strategies. -
Dexoxadrol Enantiomer
Levoxadrol is the active enantiomer of dexoxadrol, primarily targeting adrenergic receptors. This compound exhibits potent agonistic activity, making it valuable for research applications in cardiovascular and neuropharmacology studies. Its distinct biological properties facilitate investigations into adrenergic signaling pathways and their role in various physiological and pathological conditions. -
Cannabinoid Compound
Δ8-THCO (delta 8-tetrahydrocannabinol) is a cannabinoid compound derived from Cannabis sativa. This compound exhibits psychoactive properties akin to delta-9-THC, engaging with the CB1 cannabinoid receptor, which is implicated in various physiological processes such as appetite, pain sensation, and mood regulation. Δ8-THCO is utilized in research focused on understanding the effects of cannabinoids on the endocannabinoid system and exploring potential therapeutic applications in pain management and anxiety treatment. -
Peptide
Cionin is a disulfotyrosyl hybrid peptide derived from cholecystokinin and gastrin. It primarily targets cholecystokinin receptors, mediating various physiological functions such as gastric motility and enzyme secretion. This compound is utilized in research applications examining gastrointestinal physiology and the endocrine system. Its unique structure allows for the exploration of receptor interactions and signaling pathways in peptide studies. -
Nasal Vasoconstrictor
Tymazoline hydrochloride is an imidazoline derivative known for its nasal vasoconstrictor properties. It acts primarily on alpha-adrenergic receptors, leading to the reduction of nasal mucosal edema. This compound is valuable in research applications related to rhinitis and other conditions involving nasal congestion. -
Drug Derivative
MRS 2500 is a potent drug derivative that selectively targets adenosine A3 receptors. This compound exhibits significant effects on cellular signaling pathways, making it valuable for research involving inflammation and cancer biology. MRS 2500 can be utilized in studies aimed at understanding the role of adenosine receptors in various physiological and pathological processes. -
Alkaloid
N-(2-Hydroxy-3-methylbutyl)-adenosine is a natural alkaloid that modulates adenosine receptors. Its biological activity includes influencing various cellular processes such as inflammation and neuroprotection. This compound is utilized in research exploring adenosine signaling pathways and its implications in physiological and pathological conditions. -
Exenatide Impurity
(D-Asp28)-Exenatide is an impurity of Exenatide, which functions as a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist. This compound plays a significant role in the regulation of glucose homeostasis and appetite control, making it relevant for research in diabetes and obesity. The characterization of this impurity is essential for understanding the pharmacological properties and ensuring the quality of Exenatide in therapeutic applications. -
Pressor/Sympathomimetic Agent
Gepefrine is an orally active sympathomimetic agent with pressor properties. It primarily targets adrenergic receptors, enhancing vascular response and improving arterial pressure regulation. Gepefrine is utilized in research to study its effects on orthostatic dysregulation and cardiovascular dynamics. -
Biochemical Assay Reagent Control
Clenhexerol is a selective beta-adrenergic agonist that primarily targets beta-2 adrenergic receptors. This compound exhibits biological activity by stimulating smooth muscle relaxation and inducing bronchodilation. It is commonly used as a biochemical assay reagent control in research focused on respiratory diseases, pharmacological studies, and the exploration of adrenergic signaling pathways. -
Drug Derivative
Methiomeprazine is a drug derivative primarily targeting the dopaminergic system. It exhibits significant antipsychotic and sedative properties, making it valuable in the treatment of various psychiatric disorders. Methiomeprazine is commonly used in research related to neuropharmacology and the exploration of dopamine receptor interactions. Its efficacy in managing behavioral symptoms also positions it as a candidate for studies on mental health therapies. -
Biochemical Assay Reagent Control
N-Formyl desloratadine is an inhibitor targeting the H1 histamine receptor, primarily utilized as a biochemical assay reagent control. This compound demonstrates significant antihistamine activity, making it an essential tool for research related to allergic responses and histamine receptor activity. Its use in pharmacological studies allows for the assessment of H1 receptor modulation and the investigation of allergic conditions. -
Biochemical Assay Reagent
Duoperone is a neuroleptic agent that acts primarily by antagonizing dopamine receptors. This compound exhibits significant antiemetic properties in various animal models, making it valuable for studies related to nausea and psychotic disorders. Its applications extend to biochemical assays that investigate neurotransmitter dynamics and the pharmacological evaluation of antipsychotic drugs. -
Stable Isotope
3-O-Methyl Colterol-d9 is a deuterium-labeled analog of 3-O-Methyl Colterol. This stable isotope is utilized in analytical studies to track metabolic pathways and quantify interactions in biological systems. Its primary applications include pharmacokinetic studies and the investigation of drug metabolism, enhancing the understanding of biological processes involving beta-adrenergic receptors. -
Stable Isotope
Atenolol-d6 is a deuterium-labeled variant of the cardioselective β1-adrenergic receptor blocker, Atenolol. It exhibits a Ki of 697 nM at the β1-adrenoceptor in guinea pig left ventricle membranes. This stable isotope is instrumental in pharmacokinetic studies and research focused on hypertension and angina pectoris, allowing for improved metabolic tracing and analytical characterization in various biological assays. -
Stable Isotope
Desloratadine-d5 hydrochloride is a stable isotope-labeled derivative of Desloratadine hydrochloride, designed for use in quantitative mass spectrometry applications. This compound retains the pharmacological properties of the parent drug while providing a valuable tool for understanding drug metabolism and pharmacokinetics. It is particularly suitable for research in allergology and histamine receptor studies, facilitating the assessment of drug interactions and efficacy in various biological systems. -
Lipid
(−)-11-hydroxy-Δ8-THC is a phytocannabinoid that acts primarily as a cannabinoid receptor inhibitor. This compound exhibits significant biological activity in modulating lipid signaling pathways. It is utilized in research applications focused on neuropharmacology and the therapeutic potential of cannabinoids in various medical conditions.
-
Stable Isotope
N-Pentylindole-d11 is a deuterated analogue of 1-Pentyl-1H-indole, serving as a stable isotope. This compound is particularly valuable in pharmacokinetic studies, as it aids in tracing the metabolic pathways of indole-based compounds. Its application extends to the analysis of drug metabolism and the study of cannabinoid receptors, enhancing the understanding of biological mechanisms in related research fields. -
Stable Isotope
1-Oxo Colterol-d9 is a deuterium-labeled analog of 2-(Tert-butylamino)-1-(3,4-dihydroxyphenyl)ethan-1-one, serving as a stable isotope standard. This compound is valuable for quantitative mass spectrometry applications in biochemical research, particularly in studies involving adrenergic receptor signaling and pharmacokinetics. Its incorporation of deuterium enables precise tracking and analysis of metabolic pathways, enhancing the understanding of drug metabolism and activity. -
Stable Isotope
5'-Hydroxyphenyl carvedilol-d5 is a stable isotope-labeled analogue of carvedilol, targeting beta-adrenergic receptors. This deuterated compound is useful in pharmacokinetic studies, enabling the tracing of metabolic pathways and the assessment of drug disposition in various biological systems. Its structural modifications enhance the sensitivity and accuracy of analytical methods, making it an essential reagent for research applications in cardiovascular pharmacology and drug development. -
Stable Isotope
rac-Rotigotine-d3 methyl ether is a deuterium-labeled analogue of the dopamine agonist rotigotine, targeting dopamine D2 and D3 receptors. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research, enabling precise tracking of rotigotine's distribution and metabolism in biological systems. Its application enhances the understanding of dopamine receptor activity and drug interactions. -
Adrenergic Receptor Antagonist
Yohimbine-d3 is a deuterated derivative of Yohimbine, functioning as an adrenergic receptor antagonist. This compound is utilized in research to study the modulation of adrenergic signaling pathways, specifically the alpha-2 adrenergic receptors. Its applications include investigations into the effects of adrenergic blockade on physiological processes and the potential therapeutic roles in conditions such as depression and sexual dysfunction. -
Stable Isotope
Dexmedetomidine-d4 L-tartrate (-d4-major) is a deuterium-labeled derivative of Dexmedetomidine L-tartrate, serving as a stable isotope for research applications. This compound is primarily utilized in pharmacokinetic studies and metabolic labeling, enabling accurate tracking of drug disposition and action mechanisms. It supports investigations into alpha-2 adrenergic receptor modulation and sedation research, providing insights into the pharmacological properties of its parent compound. -
Stable Isotope
1H-1-Ethyl-d5 Candesartan is a deuterium-labeled derivative of 1H-1-Ethyl Candesartan, primarily utilized as a stable isotope. This compound is valuable in pharmacokinetic studies, allowing for precise tracking of drug metabolism and distribution. It aids researchers in understanding the metabolic pathways and interactions of angiotensin receptor antagonists in cardiovascular studies. -
Stable Isotope
(R)-(+)-Celiprolol-d9 hydrochloride is a deuterium-labeled analogue of the racemic beta-blocker Celiprolol, primarily targeting beta-adrenergic receptors. This stable isotope derivative facilitates precise pharmacokinetic studies and isotopic labeling experiments in chemical research. Its unique properties make it suitable for applications in metabolomics, drug metabolism, and tracer studies to elucidate the pharmacodynamics of beta-blockers. -
Stable Isotope
(Rac)-Ambrisentan-d5 is a deuterium-labeled form of (Rac)-Ambrisentan, functioning primarily as a selective endothelin receptor antagonist. Its key biological activity includes inhibition of endothelin-1, a peptide known to play a crucial role in vasoconstriction and blood pressure regulation. This stable isotope is particularly useful in pharmacokinetic studies, allowing for precise tracking of drug metabolism and distribution in biological systems. -
Stable Isotope
Apomorphine hydrochloride-d4 is a deuterium-labeled derivative of Apomorphine hydrochloride, designed as a stable isotope for metabolic studies. This compound serves as a valuable tool in pharmacokinetic and drug metabolism research, enabling precise tracking of Apomorphine in biological systems. Its application extends to studies on dopamine receptor modulation and related neurological pathways, facilitating a deeper understanding of dopaminergic signaling and its implications in various disorders. -
Stable Isotope
trans-Dihydro Tetrabenazine-d7 is a deuterium-labeled stable isotope of (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol. It serves as a valuable tool for isotopic labeling in biochemical research. Its distinct mass characteristics facilitate studies on pharmacokinetics, metabolism, and drug interactions, particularly in the context of neuropharmacology and the investigation of dopamine receptors. -
Stable Isotope
Labetalol hydrochloride-d5 is a deuterium-labeled form of Labetalol hydrochloride, specifically designed as a stable isotope for research applications. This compound functions as a selective α1-adrenergic and non-selective β-adrenergic receptor antagonist, primarily utilized for its antihypertensive properties. It is suitable for studying cardiovascular conditions, including hypertension, especially in contexts such as pregnancy where blood pressure regulation is critical. The stable isotope labeling facilitates advanced pharmacokinetic and metabolic studies. -
Drug Impurity
Ropinirole impurity 3 is a characterized impurity associated with the dopamine receptor agonist Ropinirole. This compound is crucial for assessing the purity and quality of Ropinirole in pharmaceutical formulations. It aids in the development and validation of analytical methods required for regulatory compliance in drug manufacturing. -
Drug Impurity
Tamsulosin impurity 14 is a known impurity associated with the pharmaceutical compound Tamsulosin, primarily targeting alpha-1 adrenergic receptors. This impurity is significant for quality control and analytical studies in drug development, particularly in determining the purity and stability of Tamsulosin formulations. Its characterization is essential for compliance with pharmaceutical regulations and ensuring therapeutic efficacy. -
Drug Impurity
Fluphenazine decanoate impurity 8 is a known impurity associated with Fluphenazine decanoate, an antipsychotic medication primarily targeting dopamine receptors. This compound can be utilized in analytical research to evaluate the purity of pharmaceutical formulations and support drug development processes. Its presence may affect pharmacokinetics and pharmacodynamics, making it essential for quality control and safety assessments in therapeutic applications. -
Drug Impurity
Mirabegron impurity 4 is a chemical impurity associated with the drug Mirabegron, a beta-3 adrenergic receptor agonist. This impurity is important for assessing the purity and quality of Mirabegron formulations in pharmaceutical research. Its characterization is crucial for ensuring compliance with regulatory standards and for conducting stability studies in drug development. -
Racemate
(±)-Levomepromazine is a racemic mixture primarily targeting dopamine receptors. It exhibits notable antipsychotic activity, making it relevant for research in psychiatry and neuropharmacology. Its effects on neurotransmitter pathways are valuable for studying various psychiatric disorders and the mechanisms of psychotropic agents. -
H1 Receptor Antagonist
(R)-Promethazine is an H1 receptor antagonist, serving as the R-enantiomer of Promethazine. This compound exhibits potent antihistamine activity, primarily used for its sedative effects. Additionally, it demonstrates weak antipsychotic properties, making it useful in various research applications related to sleep disorders and psychotropic effects. -
Nantenine Isomer
(R)-Nantenine is the levorotatory isomer of Nantenine, with a high affinity and selectivity for the α1A adrenergic receptor. This compound effectively blocks the behavioral suppression associated with 3,4-methylenedioxymethamphetamine (MDMA). Research applications for (R)-Nantenine primarily involve the study of disorders linked to MDMA abuse, providing valuable insights into its neuropharmacological effects. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 6-hydroxyisoquinoline isomer is a structural isomer of the synthetic cannabinoid 5-Fluoro PB-22, acting primarily as a cannabinoid receptor agonist. This compound exhibits significant binding affinity for CB1 and CB2 receptors, contributing to its potential biological effects. It can be utilized in research applications aimed at investigating the biochemical pathways and pharmacological effects of synthetic cannabinoids. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22, targeting the cannabinoid receptors. This compound exhibits significant biological activity related to the modulation of cannabinoid receptor signaling pathways. It is primarily utilized in research applications exploring cannabinoid pharmacology, drug interaction studies, and the development of therapeutic agents targeting the endocannabinoid system. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 5-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22, targeting the cannabinoid receptors. This compound has been studied for its potential biological activities within the endocannabinoid system. It may be utilized in research related to neuropharmacology and the exploration of cannabinoid receptor modulation. -
Isomer of PB-22
PB-22 6-Hydroxyquinoline isomer is a structural isomer of the cannabinoid PB-22, which primarily acts on the cannabinoid receptors. This compound may exhibit similar biological activities related to modulation of the endocannabinoid system, potentially influencing pain, inflammation, and mood regulation. It is suitable for research applications in pharmacology, toxicology, and cannabinoid receptor studies. -
Isomer of PB-22
PB-22 7-Hydroxyquinoline isomer is a structural isomer of PB-22, a synthetic cannabinoid. This compound targets cannabinoid receptors and exhibits activity that may influence the endocannabinoid system. PB-22 7-Hydroxyquinoline isomer is primarily utilized in cannabinoid research to explore its pharmacological properties and potential therapeutic applications. -
Isomer of PB-22
PB-22 8-Hydroxyisoquinoline isomer is a structural isomer of the synthetic cannabinoid PB-22. This compound acts primarily on cannabinoid receptors, modulating various signaling pathways. Its unique structure may offer insights into cannabinoid research and the development of novel therapeutic agents targeting the endocannabinoid system. PB-22 8-Hydroxyisoquinoline isomer is suitable for biochemical assays and pharmacological studies exploring cannabinoid receptor interactions. -
Isomer of PB-22
PB-22 5-Hydroxyquinoline isomer is a structural isomer of PB-22, a synthetic cannabinoid. This compound exhibits biological activity related to cannabinoid receptor modulation, making it relevant for pharmacological studies in endocannabinoid signaling pathways. Research applications include investigating the effects of synthetic cannabinoids on neural activity and their potential therapeutic uses in pain management and other neuropsychiatric conditions. -
Isomer of PB-22
PB-22 6-Hydroxyisoquinoline isomer is a structural isomer of PB-22, a synthetic cannabinoid. This compound exhibits cannabinoid receptor activity, thereby influencing endocannabinoid signaling pathways. It is primarily utilized in research settings to study the pharmacological effects of cannabinoid compounds and their potential therapeutic applications. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 N-(4-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22 that acts as a potent cannabinoid receptor agonist. This compound exhibits biological activities that may modulate cannabinoid signaling pathways, making it relevant for research in neuropharmacology and cannabinoid receptor biology. Its unique profile allows for investigations into the effects of synthetic cannabinoids on physiological and psychological processes. -
Isomer of PB-22
PB-22 5-Hydroxyisoquinoline isomer is a structural isomer of the cannabinoid PB-22, targeting cannabinoid receptors in the central nervous system. This compound exhibits potential neuropharmacological activity, making it suitable for research into cannabinoids and their effects on various biological processes. Its unique structure allows for the exploration of the functional relationships between different isomers and their associated biological activity in preclinical studies. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 6-hydroxyquinoline isomer is a structural isomer of 5-Fluoro PB-22, targeting cannabinoid receptors in the endocannabinoid system. This compound is utilized in research focused on cannabinoid receptor modulation and the investigation of its pharmacological effects. Its unique structure allows for the exploration of potential therapeutic applications and the study of receptor binding dynamics. -
Isomer of 5-Fluoro PB-22
5-Fluoro PB-22 7-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22, primarily known for its activity at cannabinoid receptors. This compound exhibits potential in studying the effects of structural variations on cannabinoid receptor function and related signaling pathways. It is applicable in research focused on pharmacology, neuroscience, and the characterization of synthetic cannabinoids.
