GPCR/G Protein

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  1. mGluR1 modulator

    CPPHA is a selective positive allosteric modulator of mGluR5 receptor.
  2. GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120).
  3. GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120).
  4. p75NTR modulator/proNGF antagonist

    LM11A-31 is a small-molecule p75NTR modulator and proNGF antagonist.
  5. PAM of mGluR4

    VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD).

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