A-1210477

Catalog No.: A15545

MCL-1 inhibitor

A-1210477

A-1210477 Chemical Structure

CAS NO. 1668553-26-1

A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks of intrinsic apoptosis and demonstrates single agent killing of multiple myeloma and non-small cell lung cancer cell lines.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$120.00
25 mg
$315.00
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Biological Activity

A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks of intrinsic apoptosis and demonstrates single agent killing of multiple myeloma and non-small cell lung cancer cell lines.
Targets
MCL-1
26.2 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.76 mL 58.82 mL 117.64 mL
0.5 mM 2.35 mL 11.76 mL 23.53 mL
1 mM 1.18 mL 5.88 mL 11.76 mL
5 mM 0.24 mL 1.18 mL 2.35 mL

*The above data is based on the productmolecular weight 850.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15545
Actions Inhibitor
M. Wt 850.04
Formula C46H55N7O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1668553-26-1
Synonyms A1210477
SMILES CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C

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