A-770041

Catalog No.: A11288

Lck inhibitor

A-770041

A-770041 Chemical Structure

CAS NO. 869748-10-7

A-770041 is selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$600.00
50 mg
$2,200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

A-770041 is selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.08 mL 80.42 mL 160.84 mL
0.5 mM 3.22 mL 16.08 mL 32.17 mL
1 mM 1.61 mL 8.04 mL 16.08 mL
5 mM 0.32 mL 1.61 mL 3.22 mL

*The above data is based on the productmolecular weight 621.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11288
Actions Inhibitor
M. Wt 621.75
Formula C34H39N9O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869748-10-7
Synonyms A770041, A 770041
SMILES CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=C(C(=N3)C5=CC(=C(C=C5)NC(=O)C6=CC7=CC=CC=C7N6C)OC)C(=NC=N4)N

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