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AAF-CMK

Catalog No.: A13605

Serine protease inhibitor

AAF-CMK

AAF-CMK Chemical Structure

CAS NO. 184901-82-4

AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI).

Availability: In stock

Package Price Qty
25 mg

Regular Price: $150.00

Special Price $120.00

50 mg

Regular Price: $250.00

Special Price $200.00

100 mg

Regular Price: $400.00

Special Price $320.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.04 mL 110.18 mL 220.36 mL
0.5 mM 4.41 mL 22.04 mL 44.07 mL
1 mM 2.2 mL 11.02 mL 22.04 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13605
Actions Inhibitor
CAS No. 184901-82-4
Formula C16H22ClN3O3.CF3COOH
M. Wt 453.8
Purity >98%
Synonyms Tripeptidyl Peptidase Inhibitor II N-Ala-Ala-Phe-CMK
SMILES C[[email protected]@H](C(=O)NC(=O)[[email protected]](C)N[[email protected]@H](CC1=CC=CC=C1)C(=O)CCl)N.C(=O)(C(F)(F)F)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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