AC220 (Quizartinib)

AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ?? 0.3 nM and >10 mM for MC4-11 and A375, respectively.
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Product Name Price Stock Qty
AC220 5mg
$50.00
In stock
AC220 10mg
$70.00
In stock
AC220 50mg
$120.00
In stock
AC220 200mg
$350.00
In stock
AC220 (Quizartinib) 10mM * 1mL in DMSO
$126.00
In stock
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Adooq Products cited in reputable paper
Adooq's AC220 (Quizartinib) has been cited by 4 publications
  • Nicholas R Anderson, .et al. , Leukemia, 2023, Mar;37(3):560-570 PMID: 36550214
  • N Naganna, .et al. , EBioMedicine, 2019, Jan 24. pii: S2352-3964(19)30012-X PMID: 30686755
  • Cong Li, .et al. , Mol Cancer Ther., 2015, Feb;14(2):375-83. PMID: 25487917
  • Yaping Zhang, .et al. , J Pharmacokinet Pharmacodyn., 2014, 41(6): 675-691 PMID: 25326874
  • Biological Activity
    Discription AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ?? 0.3 nM and >10 mM for MC4-11 and A375, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A10027
    Formula C29H32N6O4S
    Molecular Weight 560.7
    CAS Number 950769-58-1
    SMILES CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 29 mg/mL (51.72 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 15% Captisol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.83 mL 89.17 mL 178.35 mL
    0.5 mM 3.57 mL 17.83 mL 35.67 mL
    1 mM 1.78 mL 8.92 mL 17.83 mL
    5 mM 0.36 mL 1.78 mL 3.57 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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