AC220 (Quizartinib)

Catalog No.: A10027

FLT3 inhibitor

AC220 (Quizartinib)

AC220 (Quizartinib) Chemical Structure

CAS NO. 950769-58-1

AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $70.00

Special Price $56.00

50 mg

Regular Price: $120.00

Special Price $96.00

200 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO
$126.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.
Targets
FLT3 (ITD) (MV4-11 cells) FLT3 (WT) (RS4;11 cells)
1.1 nM4.2 nM
In vitro (25°C) DMSO 33.2 mg/mL (59.21 mM)
Water <0.3 mg/mL ( mM)
Ethanol <0.5 mg/mL ( mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.83 mL 89.17 mL 178.35 mL
0.5 mM 3.57 mL 17.83 mL 35.67 mL
1 mM 1.78 mL 8.92 mL 17.83 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10027
Actions Inhibitor
M. Wt 560.7
Formula C29H32N6O4S
Solubility DMSO>112mg/mL Water<1mg/mL Ethanol>4mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 950769-58-1
Synonyms N/A
SMILES CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3

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