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ADC-VI

Catalog No.: A41576
Drug-Linker Conjugates for ADC
ADC-VI is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs), utilizing Deruxtecan as the cytotoxic agent. This compound facilitates targeted delivery by chemically linking Tricyclene to an anti-FGFR2b antibody through a conjugation reaction. ADC-VI is primarily employed in research applications focused on enhancing the efficacy and selectivity of cancer therapeutics, particularly in tumors expressing FGFR2b.
ADC-VI 3031725-06-8 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionADC-VI is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs), utilizing Deruxtecan as the cytotoxic agent. This compound facilitates targeted delivery by chemically linking Tricyclene to an anti-FGFR2b antibody through a conjugation reaction. ADC-VI is primarily employed in research applications focused on enhancing the efficacy and selectivity of cancer therapeutics, particularly in tumors expressing FGFR2b.
Product Information
Catalog NumA41576
FormulaC63H77FN8O22
Molecular Weight1317.32
CAS Number3031725-06-8
SMILESCOCCOCCOCCOCCOC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)NC([C@H](C)NC([C@H](C(C)C)NC(CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(NCCN9C(C=CC9=O)=O)=O)=O)=O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC