AFG206

Name: AFG206
Brand: Adooq Bioscience
SKU: A32899
Rating: 5 (288 reviews)

Catalog No.: A32899

FLT3 Inhibitor

AFG206 is a first-generation ATP-competitive "type II" inhibitor of FLT3. This compound effectively inhibits cell proliferation with an IC50 of approximately 0.1 µM by inducing apoptosis in FLT3-ITD-Ba/F3 and D835Y-Ba/F3 cell lines. AFG206 holds significant promise for research applications related to acute myeloid leukemia.

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Grouped product items
Size	Price	Stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	AFG206 is a first-generation ATP-competitive "type II" inhibitor of FLT3. This compound effectively inhibits cell proliferation with an IC50 of approximately 0.1 µM by inducing apoptosis in FLT3-ITD-Ba/F3 and D835Y-Ba/F3 cell lines. AFG206 holds significant promise for research applications related to acute myeloid leukemia.

Product Information

Catalog Num	A32899
Formula	C20H19N3O2
Molecular Weight	333.38
CAS Number	630122-37-1
SMILES	O=C(NC1=CC=C(CC)C=C1)NC2=CC=C(C=C2)OC3=CC=NC=C3

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