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AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.25 mL | 216.26 mL | 432.53 mL |
| 0.5 mM | 8.65 mL | 43.25 mL | 86.51 mL |
| 1 mM | 4.33 mL | 21.63 mL | 43.25 mL |
| 5 mM | 0.87 mL | 4.33 mL | 8.65 mL |
*The above data is based on the productmolecular weight 231.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13587 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 116313-73-6 |
| Formula | C10H5N3O4 |
| M. Wt | 231.2 |
| Purity | >98% |
| Synonyms | AG1288, AG 1288, Tyrphostin AG 1288 |
| SMILES | C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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