AG-1288

Catalog No.: A13587

tyrosine kinase inhibitor

AG-1288 Chemical Structure

CAS NO. 116313-73-6

AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$170.00
100 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.25 mL 216.26 mL 432.53 mL
0.5 mM 8.65 mL 43.25 mL 86.51 mL
1 mM 4.33 mL 21.63 mL 43.25 mL
5 mM 0.87 mL 4.33 mL 8.65 mL

*The above data is based on the productmolecular weight 231.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13587
Actions Inhibitor
M. Wt 231.2
Formula C10H5N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 116313-73-6
Synonyms AG1288, AG 1288, Tyrphostin AG 1288
SMILES C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N

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