Biological Activity
Alofanib is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity.
In vitro | DMSO | 74 mg/mL (179 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.19 mL | 120.95 mL | 241.9 mL |
0.5 mM | 4.84 mL | 24.19 mL | 48.38 mL |
1 mM | 2.42 mL | 12.09 mL | 24.19 mL |
5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15946 |
---|---|
Actions | Inhibitor |
CAS No. | 1612888-66-0 |
Formula | C19H15N3O6S |
M. Wt | 413.4 |
Purity | >98% |
Synonyms | RPT-835, RPT 835 |
SMILES | O=[N+](C1=CC(C)=C(C2=CC=CN=C2)C=C1NS(=O)(C3=CC(C(O)=O)=CC=C3)=O)[O-] |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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