Alofanib (RPT835)

Catalog No.: A15946

FGFR2 Inhibitor

Alofanib (RPT835)

Alofanib (RPT835) Chemical Structure

CAS NO. 1612888-66-0

Alofanib is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity.

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5 mg
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Biological Activity

Alofanib is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity.
In vitro DMSO 74 mg/mL (179 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.95 mL 241.9 mL
0.5 mM 4.84 mL 24.19 mL 48.38 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15946
Actions Inhibitor
CAS No. 1612888-66-0
Formula C19H15N3O6S
M. Wt 413.4
Purity >98%
Synonyms RPT-835, RPT 835
SMILES O=[N+](C1=CC(C)=C(C2=CC=CN=C2)C=C1NS(=O)(C3=CC(C(O)=O)=CC=C3)=O)[O-]

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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