Altiratinib (DCC2701)

Catalog No.: A14387

c-Met/VEGFR inhibitor

Altiratinib (DCC2701)

Altiratinib (DCC2701) Chemical Structure

CAS NO. 1345847-93-9

Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.

Availability: In stock

Package Price Qty
5 mg
$55.00
10 mg
$80.00
25 mg
$165.00
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Biological Activity

Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.
In vitro DMSO 99 mg/mL (193.94 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.95 mL 195.9 mL
0.5 mM 3.92 mL 19.59 mL 39.18 mL
1 mM 1.96 mL 9.8 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14387
Actions Inhibitor
CAS No. 1345847-93-9
Formula C26H21F3N4O4
M. Wt 510.46
Solubility DMSO
Purity >98%
Synonyms DCC-2701, DCC2701, DCC 2701, DP 5164, DP5164, DP-5164
SMILES FC1=CC=C(NC(C2(C(NC3=C(F)C=C(OC4=CC(/N=C(O)/C5CC5)=NC=C4)C(F)=C3)=O)CC2)=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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