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AMCC-DM1

Catalog No.: A41541
Drug-Linker Conjugates for ADC
AMCC-DM1 is a drug-linker conjugate featuring the potent tubulin inhibitor DM4 and the non-cleavable linker AMCC. This compound is designed for use in antibody-drug conjugates (ADCs), facilitating targeted delivery of therapeutic agents to cancer cells. Its unique structure allows for sustained cytotoxicity while minimizing off-target effects, making AMCC-DM1 a valuable tool for research in cancer therapeutics and ADC development.
AMCC-DM1 1228105-53-0 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
500µg
$55.00
In stock
1mg
$105.00
In stock
5mg
$250.00
In stock
10mg
$380.00
In stock
25mg
$685.00
In stock
50mg
$1,005.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAMCC-DM1 is a drug-linker conjugate featuring the potent tubulin inhibitor DM4 and the non-cleavable linker AMCC. This compound is designed for use in antibody-drug conjugates (ADCs), facilitating targeted delivery of therapeutic agents to cancer cells. Its unique structure allows for sustained cytotoxicity while minimizing off-target effects, making AMCC-DM1 a valuable tool for research in cancer therapeutics and ADC development.
Product Information
Catalog NumA41541
FormulaC47H63ClN4O14S
Molecular Weight975.54
CAS Number1228105-53-0
SMILESC[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCSC(C5)C(N(CC6CCC(C(O)=O)CC6)C5=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC