AMG-176

Catalog No.: A18360

MCL-1 inhibitor

AMG-176

AMG-176 Chemical Structure

CAS NO. 1883727-34-1

AMG-176 is a potent, selective and orally bioavailable MCL-1 inhibitor, with a Ki of 0.13 nM.

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1 mg
$400.00
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Biological Activity

AMG-176 is a potent, selective and orally bioavailable MCL-1 inhibitor, with a Ki of 0.13 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.31 mL 81.54 mL 163.08 mL
0.5 mM 3.26 mL 16.31 mL 32.62 mL
1 mM 1.63 mL 8.15 mL 16.31 mL
5 mM 0.33 mL 1.63 mL 3.26 mL

*The above data is based on the productmolecular weight 613.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18360
Actions Inhibitor
M. Wt 613.21
Formula C33H41ClN2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1883727-34-1
Synonyms AMG-176; AMG 176; AMG176; tapotoclax; tapotoclaxum.
SMILES CO[[email protected]]1\C=C\C[[email protected]](C)[[email protected]@H](C)S(=O)(=O)NC(=O)c2ccc3OC[[email protected]]4(CCCc5cc(Cl)ccc45)CN(C[[email protected]@H]6CC[[email protected]@H]16)c3c2

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