AMG-Tie2-1

Catalog No.: A13456

Tie-2 inhibitor

AMG-Tie2-1

AMG-Tie2-1 Chemical Structure

CAS NO. 870223-96-4

AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM).

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$600.00
25 mg
$1,200.00
50 mg
$2,000.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.86 mL 104.29 mL 208.57 mL
0.5 mM 4.17 mL 20.86 mL 41.71 mL
1 mM 2.09 mL 10.43 mL 20.86 mL
5 mM 0.42 mL 2.09 mL 4.17 mL

*The above data is based on the productmolecular weight 479.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13456
Actions Inhibitor
M. Wt 479.45
Formula C25H20F3N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870223-96-4
Synonyms N/A
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC3=C(C=CC=N3)C4=NC(=NC=C4)NC

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