AMG232

Catalog No.: A14394

MDM2 inhibitor

AMG232

AMG232 Chemical Structure

CAS NO. 1352066-68-2

AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).

Availability: Out of stock

Package Price
5 mg
$120.00
10 mg
$200.00
25 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.94 mL 175.89 mL
0.5 mM 3.52 mL 17.59 mL 35.18 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14394
Actions Inhibitor
M. Wt 568.55
Formula C28H35Cl2NO5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1352066-68-2
Synonyms AMG-232, AMG 232
SMILES CC(C)[[email protected]@H](CS(=O)(=O)C(C)C)N1[[email protected]@H]([[email protected]](C[[email protected]](C1=O)(C)CC(=O)O)C2=CC(=CC=C2)Cl)C3=CC=C(C=C3)Cl

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