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Aminobenzenesulfonic auristatin E

Catalog No.: A41467
Drug-Linker Conjugates For ADC
Aminobenzenesulfonic auristatin E is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound exhibits potent antitumor activity through its mechanism as a cytotoxic tubulin modifier, utilizing Auristatin E linked via the aminobenzenesulfonic linker. It is valuable for research focused on enhancing targeted cancer therapies by improving the efficacy and selectivity of therapeutic agents.
Aminobenzenesulfonic auristatin E 1800462-99-0 Drug-Linker Conjugates For ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAminobenzenesulfonic auristatin E is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound exhibits potent antitumor activity through its mechanism as a cytotoxic tubulin modifier, utilizing Auristatin E linked via the aminobenzenesulfonic linker. It is valuable for research focused on enhancing targeted cancer therapies by improving the efficacy and selectivity of therapeutic agents.
Product Information
Catalog NumA41467
FormulaC37H64N6O8S
Molecular Weight753.00
CAS Number1800462-99-0
SMILESC[C@@H](C(N[S](=O)(C(C=C1)=CC=C1N)=O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)=O)OC
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC