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Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.66 mL | 103.31 mL | 206.62 mL |
| 0.5 mM | 4.13 mL | 20.66 mL | 41.32 mL |
| 1 mM | 2.07 mL | 10.33 mL | 20.66 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.13 mL |
*The above data is based on the productmolecular weight 483.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21503 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1055986-67-8 |
| Formula | C23H21N5O3S.xHCl |
| M. Wt | 483.97 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | MP470 hydrochloride, MP 470, MP-470; HPK 56 hydrochloride, HPK56, HPK-56 |
| SMILES | S=C(N1CCN(C2=C3OC4=CC=CC=C4C3=NC=N2)CC1)NCC5=CC=C6OCOC6=C5.[x].Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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