The Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody that exhibits high-affinity binding to insulin-like growth factor-binding protein 2 (IGFBP2). This antibody effectively inhibits the interaction between IGFBP2 and insulin-like growth factor 1 (IGF1), thereby blocking IGFBP2's biological activity. The Anti-IGFBP2 Antibody (M14) has been demonstrated to inhibit endothelial cell recruitment, a critical process in tumor angiogenesis and metastasis, thereby impeding the progression of human metastatic cancers. This product is pivotal for research focused on cancer biology, particularly in studies exploring mechanisms of tumor growth and metastasis.
The Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody that exhibits high-affinity binding to insulin-like growth factor-binding protein 2 (IGFBP2). This antibody effectively inhibits the interaction between IGFBP2 and insulin-like growth factor 1 (IGF1), thereby blocking IGFBP2's biological activity. The Anti-IGFBP2 Antibody (M14) has been demonstrated to inhibit endothelial cell recruitment, a critical process in tumor angiogenesis and metastasis, thereby impeding the progression of human metastatic cancers. This product is pivotal for research focused on cancer biology, particularly in studies exploring mechanisms of tumor growth and metastasis.
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Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
Frequently Asked Questions
What are Biosimilar Antibodies?
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research.
Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
