Aprutumab ixadotin is an antibody-drug conjugate (ADC) that targets fibroblast growth factor receptor 2 (FGFR2). It combines a fully human anti-FGFR2 monoclonal antibody with an innovative non-cleavable linker conjugated to an Auristatin W derivative. This reagent is primarily utilized in research focused on advanced solid tumors, including FGFR2-positive gastric cancer and triple-negative breast cancer, facilitating the exploration of targeted therapies in these malignancies.
Aprutumab ixadotin is an antibody-drug conjugate (ADC) that targets fibroblast growth factor receptor 2 (FGFR2). It combines a fully human anti-FGFR2 monoclonal antibody with an innovative non-cleavable linker conjugated to an Auristatin W derivative. This reagent is primarily utilized in research focused on advanced solid tumors, including FGFR2-positive gastric cancer and triple-negative breast cancer, facilitating the exploration of targeted therapies in these malignancies.
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