ARQ 197 (Tivantinib)

Catalog No.: A11087

c-Met inhibitor

ARQ 197 (Tivantinib)

ARQ 197 (Tivantinib) Chemical Structure

CAS NO. 1000873-98-2, 905854-02-6

ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase

Availability: In stock

Package Price Qty
10 mg
$90.00
50 mg
$240.00
100 mg
$350.00
200 mg
$580.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Wang L, .et al. Bispecific Aptamer Induced Artificial Protein-Pairing: A Strategy for Selective Inhibition of Receptor Function, J Am Chem Soc, 2019, Aug 14;141(32):12673-12681 PMID: 31381313
  • Koide H, .et al. Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1, Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773

Biological Activity

ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase
In vitro DMSO 69 mg/mL (186.77 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.35 mL 270.71 mL
0.5 mM 5.41 mL 27.07 mL 54.14 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11087
Actions Inhibitor
CAS No. 1000873-98-2, 905854-02-6
Formula C23H19N3O2
M. Wt 369.4
Purity >98%
Synonyms ARQ197
SMILES C1CC2=CC=CC3=C2N(C1)C=C3[[email protected]]4[[email protected]@H](C(=O)NC4=O)C5=CNC6=CC=CC=C65
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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