Asciminib
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Asciminib (ABL001) is a potent and selective allosteric Bcr-Abl inhibitor; inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. |
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Catalog Num | A19658 |
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Formula | C20H18ClF2N5O3 |
Molecular Weight | 449.84 |
CAS Number | 1492952-76-7 |
SMILES | O=C(C1=CC(C2=NNC=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4 |
Synonyms | ABL001, ABL 001, ABL-001 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 76 mg/mL (168.94 mM) | |
Ethanol | 76 mg/mL (168.94 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.23 mL | 111.15 mL | 222.3 mL |
0.5 mM | 4.45 mL | 22.23 mL | 44.46 mL |
1 mM | 2.22 mL | 11.12 mL | 22.23 mL |
5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2