ASP3026

Catalog No.: A11773

ALK inhibitor

ASP3026

ASP3026 Chemical Structure

CAS NO. 1097917-15-1

ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase activity and was more selective than crizotinib in a Tyr-kinase panel.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$180.00
50 mg
$300.00
10mM * 1mL in DMSO
$90.00
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Biological Activity

ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase activity and was more selective than crizotinib in a Tyr-kinase panel.
Targets
ALK
3.5 nM
In vitro DMSO 13 mg/mL (22.38 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.22 mL 86.1 mL 172.21 mL
0.5 mM 3.44 mL 17.22 mL 34.44 mL
1 mM 1.72 mL 8.61 mL 17.22 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 580.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11773
Actions Inhibitor
CAS No. 1097917-15-1
Formula C29H40N8O3S
M. Wt 580.7
Purity >98%
Synonyms ASP 3026, ASP-3026
SMILES CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC=NC(=N2)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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