AT101 acetic acid

Name: AT101 acetic acid
SKU: A13578
Price: 25 USD
Rating: 5 (288 reviews)

Catalog No.: A13578

pan Bcl-2 inhibitor

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID

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Grouped product items
Size	Price	Stock
2mg	$25.00	In stock
5mg	$45.00	In stock
10mg	$80.00	In stock
25mg	$170.00	In stock
50mg	$290.00	In stock
100mg	$480.00	In stock
500mg	$1,055.00	In stock
1g	$1,425.00	In stock
*10mM 1mL in DMSO**	$117.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID

Targets

Target	Value

Product Information

Catalog Num	A13578
Formula	C30H30O8.C2H4O2
Molecular Weight	578.61
CAS Number	866541-93-7
SMILES	CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O
Synonyms	AT-101, AT 101
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	108 mg/mL (186.65 mM)
	Water	Insoluble
	Ethanol	83 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.28 mL	86.41 mL	172.83 mL
0.5 mM	3.46 mL	17.28 mL	34.57 mL
1 mM	1.73 mL	8.64 mL	17.28 mL
5 mM	0.35 mL	1.73 mL	3.46 mL

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