AVL-292 benzenesulfonate

Catalog No.: A15008

BTK inhibitor

AVL-292 benzenesulfonate

AVL-292 benzenesulfonate Chemical Structure

CAS NO. 1360053-81-1

AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.

Availability: In stock

Package Price Qty
10 mg
$120.00
50 mg
$350.00
100 mg
$540.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.19 mL 85.97 mL 171.93 mL
0.5 mM 3.44 mL 17.19 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.19 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15008
Actions Inhibitor
M. Wt 581.62
Formula C28H28FN5O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1360053-81-1
Synonyms AVL292 benzenesulfonate, AVL 292 benzenesulfonate
SMILES COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O

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