AZD 2932

Catalog No.: A14156

mutil-targeted protein tyrosine kinase inhibitor

AZD 2932

AZD 2932 Chemical Structure

CAS NO. 883986-34-3

AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
25 mg
$240.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively.
Targets
PDGFRβ Flt3 VEGFR-2 c-Kit
4 nM7 nM8 nM9 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.35 mL 111.73 mL 223.47 mL
0.5 mM 4.47 mL 22.35 mL 44.69 mL
1 mM 2.23 mL 11.17 mL 22.35 mL
5 mM 0.45 mL 2.23 mL 4.47 mL

*The above data is based on the productmolecular weight 447.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14156
Actions Inhibitor
M. Wt 447.49
Formula C24H25N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 883986-34-3
Synonyms AZD-2932,AZD2932
SMILES CC(C)N1C=C(C=N1)NC(=O)CC2=CC=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC

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