BAM 7

Catalog No.: A12907

Bax activator

BAM 7

BAM 7 Chemical Structure

CAS NO. 331244-89-4

BAM 7 binds the BAX trigger site with an EC50 ~ 3.3 μM as measured in a competitive FP assay using FITC-BIM SAHB and BAX.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$90.00
25 mg
$180.00
50 mg
$350.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Takino JI, .et al. The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells, Sci Rep, 2019, Nov 13;9(1):16717 PMID: 31723205

Biological Activity

BAM 7 binds the BAX trigger site with an EC50 ~ 3.3 μM as measured in a competitive FP assay using FITC-BIM SAHB and BAX.
Targets
Bax
3.3 μM(EC50)
In vitro DMSO 2 mg/mL (4.93 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.66 mL 123.31 mL 246.63 mL
0.5 mM 4.93 mL 24.66 mL 49.33 mL
1 mM 2.47 mL 12.33 mL 24.66 mL
5 mM 0.49 mL 2.47 mL 4.93 mL

*The above data is based on the productmolecular weight 405.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12907
Actions Activator
CAS No. 331244-89-4
Formula C21H19N5O2S
M. Wt 405.47
Purity >98%
Synonyms BAM7
SMILES CCOC1=CC=CC=C1N/N=C/2\C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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