BCR-ABL-IN-2

Catalog No.: A21043

BCR-ABL inhibitor

BCR-ABL-IN-2

BCR-ABL-IN-2 Chemical Structure

CAS NO. 897369-18-5

BCR-ABL-IN-2 is an inhibitor of BCR-ABL1 tyrosine kinase, with IC50s of 57 nM, 773 nm for ABL1native and ABL1T315I, respectively.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

BCR-ABL-IN-2 is an inhibitor of BCR-ABL1 tyrosine kinase, with IC50s of 57 nM, 773 nm for ABL1native and ABL1T315I, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.9 mL 99.52 mL 199.05 mL
0.5 mM 3.98 mL 19.9 mL 39.81 mL
1 mM 1.99 mL 9.95 mL 19.9 mL
5 mM 0.4 mL 1.99 mL 3.98 mL

*The above data is based on the productmolecular weight 502.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21043
Actions Inhibitor
CAS No. 897369-18-5
Formula C24H25Cl2N5O3
M. Wt 502.39
Purity >98%
SMILES O=C([[email protected]]1NCC2=C(C=C(N3N=C(C(C)(C)C)C=C3NC(NC4=CC=CC(Cl)=C4Cl)=O)C=C2)C1)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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