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Biological Activity
Kanamycin B is an inhibitor of protein translation and mammalian RNA splicing. It inhibits growth of gram negative bacteria, prevents formulation of the initiation complex, and decreases action potential amplitude in cardiac pacemaker cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.68 mL | 103.41 mL | 206.82 mL |
| 0.5 mM | 4.14 mL | 20.68 mL | 41.36 mL |
| 1 mM | 2.07 mL | 10.34 mL | 20.68 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
*The above data is based on the productmolecular weight 483.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18158 |
|---|---|
| CAS No. | 4696-76-8 |
| Formula | C18H37N5O10 |
| M. Wt | 483.51 |
| Purity | >98% |
| Synonyms | Bekanamycin; NK-1006; NK1006; NK 1006; Nebramycin V |
| SMILES | NC[C@H]1O[C@@H]([C@@H]([C@H]([C@@H]1O)O)N)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)N)O)CO)N)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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