BGB-8035 is a highly selective bruton's tyrosine kinase (BTK) inhibitor, exhibiting an IC50 of 1.1 nM for BTK, while demonstrating lower activity against TEC and EGFR with IC50 values of 99 nM and 621 nM, respectively. This compound displays significant antitumor and anti-arthritis properties, making it a valuable tool for investigating B-cell malignancies and autoimmune diseases. BGB-8035 is ideal for research applications focused on targeted therapies in hematological tumors and related pathologies.
BGB-8035 is a highly selective bruton's tyrosine kinase (BTK) inhibitor, exhibiting an IC50 of 1.1 nM for BTK, while demonstrating lower activity against TEC and EGFR with IC50 values of 99 nM and 621 nM, respectively. This compound displays significant antitumor and anti-arthritis properties, making it a valuable tool for investigating B-cell malignancies and autoimmune diseases. BGB-8035 is ideal for research applications focused on targeted therapies in hematological tumors and related pathologies.
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