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Catalog No.: A15534

FGFR inhibitor


BLU9931 Chemical Structure

CAS NO. 1538604-68-0

BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),

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Biological Activity

BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),
3 nM150 nM493 nM591 nM
In vitro (25°C) DMSO Warmed: 4 mg/mL (7.85 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% carboxymethylcellulose+1% Tween 80 as a suspension 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.63 mL 98.16 mL 196.32 mL
0.5 mM 3.93 mL 19.63 mL 39.26 mL
1 mM 1.96 mL 9.82 mL 19.63 mL
5 mM 0.39 mL 1.96 mL 3.93 mL

*The above data is based on the productmolecular weight 509.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15534
Actions Inhibitor
CAS No. 1538604-68-0
Formula C26H22Cl2N4O3
M. Wt 509.38
Purity >98%
Synonyms BLU-9931, BLU 9931

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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