BLZ945

Catalog No.: A15540

CSF1R inhibitor

BLZ945

BLZ945 Chemical Structure

CAS NO. 953769-46-5

BLZ945 is a potent and selective CSF-1R kinase inhibitor. It attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $150.00

Special Price $135.00

25 mg

Regular Price: $280.00

Special Price $252.00

50 mg

Regular Price: $450.00

Special Price $405.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BLZ945 is a potent and selective CSF-1R kinase inhibitor. It attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas.
Targets
CSF-1R
1 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.1 mL 125.5 mL 251 mL
0.5 mM 5.02 mL 25.1 mL 50.2 mL
1 mM 2.51 mL 12.55 mL 25.1 mL
5 mM 0.5 mL 2.51 mL 5.02 mL

*The above data is based on the productmolecular weight 398.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15540
Actions Inhibitor
M. Wt 398.4
Formula C20H22N4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 953769-46-5
Synonyms BLZ 945, BLZ-945
SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O

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