Catalog No.: A12743

Bcl-2/Bcl-xL inhibitor


BM-1074 Chemical Structure

CAS NO. 1391108-10-3

BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.

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Biological Activity

BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.87 mL 49.33 mL 98.65 mL
0.5 mM 1.97 mL 9.87 mL 19.73 mL
1 mM 0.99 mL 4.93 mL 9.87 mL
5 mM 0.2 mL 0.99 mL 1.97 mL

*The above data is based on the productmolecular weight 1013.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12743
Actions Inhibitor
CAS No. 1391108-10-3
Formula C50H57ClN8O7S3
M. Wt 1013.68
Purity >98%
Synonyms BM1074, BM 1074
SMILES CC1=C(C(=C(N1C(C)C)C2=CC=C(C=C2)Cl)C3=CC(=CC=C3)N4CCN(CC4)C5=CC=C(C=C5)NS(=O)(=O)C6=CC(=C(C=C6)NC(CCN(C)C)CSC7=CC=CC=C7)[N+](=O)[O-])C(=O)NS(=O)(=O)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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