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Bcl-2/Bcl-xL inhibitor

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Catalog No. A12743

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BM-1074 10mg A12743-10
BM-1074 25mg A12743-25
BM-1074 50mg A12743-50
BM-1074 100mg A12743-100

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.


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Chemical Information

Catalog Num A12743
Actions Inhibitor
M. Wt 1013.68
Formula C50H57ClN8O7S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1391108-10-3
Synonyms BM1074, BM 1074
SMILES CC1=C(C(=C(N1C(C)C)C2=CC=C(C=C2)Cl)C3=CC(=CC=C3)N4CCN(CC4)C5=CC=C(C=C5)NS(=O)(=O)C6=CC(=C(C=C6)NC(CCN(C)C)CSC7=CC=CC=C7)[N+](=O)[O-])C(=O)NS(=O)(=O)C

Biological Activity

BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.87 mL 49.33 mL 98.65mL
0.5 mM 1.97 mL 9.87 mL 19.73 mL
1 mM 0.99 mL 4.93 mL 9.87 mL
5 mM 0.2 mL 0.99 mL 1.97 mL

*The above data is based on the productmolecular weight 1013.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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