BMS-986021, also known as BMS-986148 antibody, is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets Mesothelin, a protein frequently overexpressed in various forms of cancer, making it a valuable tool for oncological research. This antibody comprises a human IgG1 heavy chain and a human kappa light chain, with a predicted molecular weight of 144.46 kDa. For experiments requiring an isotype control, the Human IgG1 kappa Isotype Control is recommended to accurately assess the antibody's specificity and ensure robust experimental results.
BMS-986021, also known as BMS-986148 antibody, is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets Mesothelin, a protein frequently overexpressed in various forms of cancer, making it a valuable tool for oncological research. This antibody comprises a human IgG1 heavy chain and a human kappa light chain, with a predicted molecular weight of 144.46 kDa. For experiments requiring an isotype control, the Human IgG1 kappa Isotype Control is recommended to accurately assess the antibody's specificity and ensure robust experimental results.
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Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
Frequently Asked Questions
What are Biosimilar Antibodies?
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research.
Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
