BMS-986142

Catalog No.: A19993
BTK inhibitor
BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.
Grouped product items
Product Name Price Stock Qty
BMS-986142 5mg
$220.00
In stock
BMS-986142 10mg
$720.00
In stock
BMS-986142 50mg
$2,280.00
In stock
BMS-986142 100mg
$3,280.00
In stock
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Biological Activity
Discription BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.
Product Information
Catalog Num A19993
Formula C32H30F2N4O4
Molecular Weight 572.6
CAS Number 1643368-58-4
SMILES O=C1C2=C(C(F)=CC=C2)N(C)C(N1C3=C(C)[C@]([C@]4=C(F)C=C(C(N)=O)C5=C4C6=C(C[C@@H](C(C)(C)O)CC6)N5)=CC=C3)=O
Synonyms BMS986142, BMS 986142
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (155.43 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.46 mL 87.32 mL 174.64 mL
0.5 mM 3.49 mL 17.46 mL 34.93 mL
1 mM 1.75 mL 8.73 mL 17.46 mL
5 mM 0.35 mL 1.75 mL 3.49 mL
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