BMS-986142
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. |
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Catalog Num | A19993 |
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Formula | C32H30F2N4O4 |
Molecular Weight | 572.6 |
CAS Number | 1643368-58-4 |
SMILES | O=C1C2=C(C(F)=CC=C2)N(C)C(N1C3=C(C)[C@]([C@]4=C(F)C=C(C(N)=O)C5=C4C6=C(C[C@@H](C(C)(C)O)CC6)N5)=CC=C3)=O |
Synonyms | BMS986142, BMS 986142 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (155.43 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.46 mL | 87.32 mL | 174.64 mL |
0.5 mM | 3.49 mL | 17.46 mL | 34.93 mL |
1 mM | 1.75 mL | 8.73 mL | 17.46 mL |
5 mM | 0.35 mL | 1.75 mL | 3.49 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2