BPR1J-340

Name: BPR1J-340
Brand: Adooq Bioscience
SKU: A33038
Rating: 5 (288 reviews)

Catalog No.: A33038

FLT3 Inhibitor

BPR1J-340 is a potent inhibitor of FLT3, exhibiting an IC50 of approximately 25 nM. It effectively inhibits the phosphorylation of FLT3 and STAT5, inducing apoptosis in FLT3-ITD positive acute myeloid leukemia (AML) cells. This compound demonstrates considerable anti-tumor activities, making it a valuable tool for research in cancer biology and therapeutic strategies targeting FLT3 dysregulation.

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Grouped product items
Size	Price	Stock
25mg	$1,530.00	In stock
50mg	$1,950.00	In stock
100mg	$2,480.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	BPR1J-340 is a potent inhibitor of FLT3, exhibiting an IC50 of approximately 25 nM. It effectively inhibits the phosphorylation of FLT3 and STAT5, inducing apoptosis in FLT3-ITD positive acute myeloid leukemia (AML) cells. This compound demonstrates considerable anti-tumor activities, making it a valuable tool for research in cancer biology and therapeutic strategies targeting FLT3 dysregulation.

Product Information

Catalog Num	A33038
Formula	C29H34N8O3
Molecular Weight	542.63
CAS Number	1395051-72-5
SMILES	O=C(NC1=NNC(C2=CC=C(CNC(NC3=NOC(CC)=C3)=O)C=C2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4

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