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Btk inhibitor 1 R enantiomer hydrochloride

Catalog No.: A21865

BTK inhibitor

Btk inhibitor 1 R enantiomer hydrochloride

Btk inhibitor 1 R enantiomer hydrochloride Chemical Structure

CAS NO. 1553977-42-6

Btk inhibitor 1 R enantiomer hydrochloride (Ibrutinib analog hydrochloride) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $378.00

Special Price $302.40

10 mg

Regular Price: $651.00

Special Price $520.80

50 mg

Regular Price: $1,932.00

Special Price $1,545.60

100 mg

Regular Price: $3,864.00

Special Price $3,091.20

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Btk inhibitor 1 R enantiomer hydrochloride (Ibrutinib analog hydrochloride) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.65 mL 118.23 mL 236.46 mL
0.5 mM 4.73 mL 23.65 mL 47.29 mL
1 mM 2.36 mL 11.82 mL 23.65 mL
5 mM 0.47 mL 2.36 mL 4.73 mL

*The above data is based on the productmolecular weight 422.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21865
Actions Inhibitor
CAS No. 1553977-42-6
Formula C22H23ClN6O
M. Wt 422.91
Purity >98%
Synonyms Ibrutinib analog hydrochloride
SMILES NC1=C2C(N([[email protected]]3CNCCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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