BTSA1

Catalog No.: A16835

Bcl-2 modulator

BTSA1

BTSA1 Chemical Structure

CAS NO. 314761-14-3

BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$180.00
10 mg
$320.00
50 mg
$1,200.00
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Biological Activity

BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.14 mL 232.28 mL
0.5 mM 4.65 mL 23.23 mL 46.46 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16835
Actions Modulator
M. Wt 430.51
Formula C21H14N6OS2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 314761-14-3
SMILES O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5

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