BTSA1

Catalog No.: A16835
Bcl-2 modulator
BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
Grouped product items
Product Name Price Stock Qty
BTSA1 2mg
$70.00
In stock
BTSA1 5mg
$120.00
In stock
BTSA1 10mg
$190.00
In stock
BTSA1 50mg
$580.00
In stock
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Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
Targets
Target Value
Product Information
Catalog Num A16835
Formula C21H14N6OS2
Molecular Weight 430.51
CAS Number 314761-14-3
SMILES O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 77 mg/mL (178.85 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.14 mL 232.28 mL
0.5 mM 4.65 mL 23.23 mL 46.46 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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