Cediranib (AZD2171)

Cediranib (AZD2171) Chemical Structure

CAS NO. 288383-20-0

Cediranib (AZD2171) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $36.00

10 mg

Regular Price: $75.00

Special Price $67.50

50 mg

Regular Price: $280.00

Special Price $252.00

100 mg

Regular Price: $420.00

Special Price $378.00

10mM * 1mL in DMSO

Regular Price: $95.00

Special Price $85.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Cediranib (AZD2171) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.
Target Value
c-KitIC50: 2nM
VEGFR3/FLT4IC50: <=3nM
FGFR1IC50: 26nM
PDGFRαIC50: 36nM
CSF-1RIC50: 110nM
SrcIC50: 130nM
AblIC50: 260nM
FLT3IC50: >1μM
HER2/ErbB2IC50: >1μM
CDK2IC50: >1μM
CDK4IC50: >1μM
EGFRIC50: 1.6μM
AuroraAIC50: >10μM
AuroraBIC50: >10μM
MEKIC50: >10μM
In vitro (25°C) DMSO 90 mg/mL (199.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.2 mL 110.99 mL 221.98 mL
0.5 mM 4.44 mL 22.2 mL 44.4 mL
1 mM 2.22 mL 11.1 mL 22.2 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10185
Actions Inhibitor
M. Wt 450.5
Formula C25H27FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 288383-20-0
Synonyms Recentin

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