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Biological Activity
CEP-28122 is a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.55 mL | 92.75 mL | 185.51 mL |
| 0.5 mM | 3.71 mL | 18.55 mL | 37.1 mL |
| 1 mM | 1.86 mL | 9.28 mL | 18.55 mL |
| 5 mM | 0.37 mL | 1.86 mL | 3.71 mL |
*The above data is based on the productmolecular weight 539.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13744 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1022958-60-6 |
| Formula | C28H35ClN6O3 |
| M. Wt | 539.06 |
| Purity | >98% |
| Synonyms | CEP28122, CEP 28122 |
| SMILES | COC1=C(C=CC2=C1CCC(CC2)N3CCOCC3)NC4=NC=C(C(=N4)NC5C6CC(C5C(=O)N)C=C6)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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