CEP-37440

Catalog No.: A15543

FAK/ALK inhibitor

CEP-37440

CEP-37440 Chemical Structure

CAS NO. 1391712-60-9

CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).

Availability: In stock

Package Price Qty
5 mg
$95.00
10 mg
$160.00
25 mg
$380.00
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Biological Activity

CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.24 mL 86.19 mL 172.38 mL
0.5 mM 3.45 mL 17.24 mL 34.48 mL
1 mM 1.72 mL 8.62 mL 17.24 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15543
Actions Inhibitor
CAS No. 1391712-60-9
Formula C30H38ClN7O3
M. Wt 580.12
Purity >98%
Synonyms CEP37440, CEP 37440
SMILES CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C4=C(CC(CCC4)N5CCN(CC5)CCO)C=C3)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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