CEP-40783

Catalog No.: A20331
AXL/c-Met inhibitor
CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
Grouped product items
Product Name Price Stock Qty
CEP-40783 5mg
$80.00
In stock
CEP-40783 10mg
$120.00
In stock
CEP-40783 50mg
$420.00
In stock
CEP-40783 100mg
$600.00
In stock
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Biological Activity
Discription CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
Product Information
Catalog Num A20331
Formula C31H26F2N4O6
Molecular Weight 588.56
CAS Number 1437321-24-8
SMILES O=C(C1=CN(C(C)C)C(N(C2=CC=C(F)C=C2)C1=O)=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C(F)=C3
Synonyms CEP 40783, CEP40783; RXDX-106, RXDX106, RXDX 106
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 9 mg/mL (15.29 mM)
Water Insoluble
Ethanol 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.99 mL 84.95 mL 169.91 mL
0.5 mM 3.4 mL 16.99 mL 33.98 mL
1 mM 1.7 mL 8.5 mL 16.99 mL
5 mM 0.34 mL 1.7 mL 3.4 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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