CHMFL-KIT-033

Catalog No.: A18476

c-KIT T670I mutant inhibitor

CHMFL-KIT-033

CHMFL-KIT-033 Chemical Structure

CAS NO. 2351801-41-5

CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.36 mL 240.72 mL
0.5 mM 4.81 mL 24.07 mL 48.14 mL
1 mM 2.41 mL 12.04 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18476
Actions Inhibitor
M. Wt 415.42
Formula C23H18FN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2351801-41-5
SMILES O=C(CC(NC1=CC=CC(F)=C1)=O)NC2=CC(NN=C3/C=C/C4=CC=CC=N4)=C3C=C2

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