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Biological Activity
CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.07 mL | 120.36 mL | 240.72 mL |
0.5 mM | 4.81 mL | 24.07 mL | 48.14 mL |
1 mM | 2.41 mL | 12.04 mL | 24.07 mL |
5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18476 |
---|---|
Actions | Inhibitor |
CAS No. | 2351801-41-5 |
Formula | C23H18FN5O2 |
M. Wt | 415.42 |
Purity | >98% |
SMILES | O=C(CC(NC1=CC=CC(F)=C1)=O)NC2=CC(NN=C3/C=C/C4=CC=CC=N4)=C3C=C2 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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