COTI-2

Catalog No.: A16974

COTI-2

COTI-2 Chemical Structure

CAS NO. 1039455-84-9

COTI-2 is an orally available thiosemicarbazone that activates mutant forms of p53. It induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar concentrations.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
50 mg
$560.00
100 mg
$760.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

COTI-2 is an orally available thiosemicarbazone that activates mutant forms of p53. It induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar concentrations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.43 mL 272.85 mL
0.5 mM 5.46 mL 27.29 mL 54.57 mL
1 mM 2.73 mL 13.64 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16974
M. Wt 366.5
Formula C19H22N6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1039455-84-9
Synonyms COTI2, COTI 2
SMILES S=C(N/N=C1C(N=CC=C2)=C2CCC\1)N(CC3)CCN3C4=NC=CC=C4

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy COTI-2 | COTI-2 Supplier | purchase | cost | manufacturer | order | distributor | buy 1039455-84-9| 1039455-84-9 Supplier | purchase 1039455-84-9 | 1039455-84-9 cost | 1039455-84-9 manufacturer | order 1039455-84-9 | 1039455-84-9 distributor
Rewards