CP-547632 TFA is a potent, orally active inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) and Fibroblast Growth Factor (FGF) kinases, exhibiting IC50 values of 11 nM and 9 nM, respectively. This reagent demonstrates notable selectivity for VEGFR-2 and bFGF over other tyrosine kinases, including EGFR and PDGFRβ. CP-547632 TFA is primarily utilized in cancer research due to its antitumor efficacy, making it a valuable tool for studies focused on angiogenesis and tumor development.
CP-547632 TFA is a potent, orally active inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) and Fibroblast Growth Factor (FGF) kinases, exhibiting IC50 values of 11 nM and 9 nM, respectively. This reagent demonstrates notable selectivity for VEGFR-2 and bFGF over other tyrosine kinases, including EGFR and PDGFRβ. CP-547632 TFA is primarily utilized in cancer research due to its antitumor efficacy, making it a valuable tool for studies focused on angiogenesis and tumor development.
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