CP-673451
CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's CP-673451 has been cited by 1 publications
- Kaori Aoto, .et al. , Oncotarget, 2018, Sep 25; 9(75): 34090-34102 PMID: 30344924
Biological Activity
| Description | CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM. | ||
|---|---|---|---|
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Product Information
| Catalog Num | A11350 |
|---|---|
| Formula | C24H27N5O2 |
| Molecular Weight | 417.5 |
| CAS Number | 343787-29-1 |
| SMILES | COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3 |
| Synonyms | CP673451 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | Warmed: 28 mg/mL (67.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL | ||
| In vivo | 5%DMSO+40%PEG300+5%Tween80+50%ddH2O | 2.3 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.95 mL | 119.76 mL | 239.52 mL |
| 0.5 mM | 4.79 mL | 23.95 mL | 47.9 mL |
| 1 mM | 2.4 mL | 11.98 mL | 23.95 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.79 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
