D-65476 is a selective inhibitor of the Flt3 receptor tyrosine kinase, primarily acting in the absence of IL-3. It effectively suppresses the proliferation of TEL-Flt3 transfected BA/F3 cells, demonstrating an IC50 value of 0.2 μM. This compound is a valuable tool for exploring Flt3-driven leukemias and related therapeutic strategies.
D-65476 is a selective inhibitor of the Flt3 receptor tyrosine kinase, primarily acting in the absence of IL-3. It effectively suppresses the proliferation of TEL-Flt3 transfected BA/F3 cells, demonstrating an IC50 value of 0.2 μM. This compound is a valuable tool for exploring Flt3-driven leukemias and related therapeutic strategies.
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