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DBM-C5-VC-PAB-MMAE

Catalog No.: A41374
Drug-Linker Conjugate for ADC
DBM-C5-VC-PAB-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It consists of a C5-VC-PAB linker coupled with a maleimide functional group and the potent cytotoxic agent MMAE. This conjugate is utilized in targeted cancer therapies, enhancing the selective delivery of MMAE to tumor cells while minimizing systemic exposure. Its unique structural components facilitate effective conjugation to antibodies, paving the way for innovative approaches in oncology research.
DBM-C5-VC-PAB-MMAE 1644228-55-6 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$270.00
In stock
5mg
$695.00
In stock
10mg
$1,140.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBM-C5-VC-PAB-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It consists of a C5-VC-PAB linker coupled with a maleimide functional group and the potent cytotoxic agent MMAE. This conjugate is utilized in targeted cancer therapies, enhancing the selective delivery of MMAE to tumor cells while minimizing systemic exposure. Its unique structural components facilitate effective conjugation to antibodies, paving the way for innovative approaches in oncology research.
Product Information
Catalog NumA41374
FormulaC68H103Br2N11O15
Molecular Weight1474.42
CAS Number1644228-55-6
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C(Br)=C(C4=O)Br)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC